If you would like to explore the possibility of participating in a clinical trial at Guthrie, please call 1-800-836-0388.

As a Guthrie cancer patient you will have the unique opportunity to participate in one or more of some 100 clinical research trials that involve new treatments for many cancer types.

As a Guthrie patient you may have the unique opportunity to take part in clinical research trials for atrial fibrillation, congestive heart failure, lipid disorders, heart attack and many more cardiology disease states.

As a Guthrie patient you may have an opportunity to take part in clinical research trials for celiac disease, Crohn’s disease, ulcerative colitis, reflux disease, hepatitis and many more gastroenterology disease states.

Clinical trials study new ways to prevent, detect and treat disease. If you take part in research, you help advance new investigational medical therapies. 

Title: NRG-LU007: Randomized Phase II/III Trial of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR Trial
Department: Oncology
Diagnosis: Lung- Small Cell
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: NRG
Details (Indentifier #): NCT04402788
Title: OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy
Department: Oncology
Diagnosis: Breast
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: ALLIANCE
Details (Indentifier #): NCT05812807
Title: Preserve-003: Phase 3, Two-stage, Randomized Study of ONC-392 Versus Docetaxel in Metastatic Non-Small Cell Lung Cancers that Progressed on PD-1/PD-L1 Inhibitors
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: OncoC4
Details (Indentifier #): NCT05671510
Title: S-11: A multicentre, prospective clinical study analysing outcomes of shoulder arthroplasty with SMR TT Hybrid Glenoid with or without SMR Cementless Finned Short Stem
Department: Orthopedic Surgery
Diagnosis: Orthopedics
Principal Investigator: Joseph Y. Choi, MD, PhD, MHA
Sponsors: Lima
Details (Indentifier #): NCT05314387
Title: S1706: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy Versus Radiotherapy Alone for Inflammatory Breast Cancer
Department: Oncology
Diagnosis: Breast- Adjuvant
Principal Investigator: Thomas J Gergel, MD
Sub-Investigator(s):
Sponsors: SWOG
Details (Indentifier #): NCT03598257
Title: S1827: MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)
Department: Oncology
Diagnosis: Lung- Small Cell
Principal Investigator: Thomas J Gergel, MD
Sponsors: SWOG
Details (Indentifier #): NCT04155034
Title: S2015: Melanoma Margins Trial (MelMarT): A Phase III, Multi-Centre, Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma
Department: Oncology
Diagnosis: Melanoma
Principal Investigator: David Bertsch, MD, FACS
Sponsors: SWOG
Details (Indentifier #): NCT03860883
Title: SALIX RNLC3131, A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C)
Department: Gastroenterology
Diagnosis: Gastrointestinal - Liver
Principal Investigator: Thomas J McDonald, MD
Sponsors: Salix
Details (Indentifier #): NCT05071716
Title: Tethered Enzyme Technology (TET) Assay for
Detection of COVID-19
Department: Internal Studies
Diagnosis: Infectious Disease
Principal Investigator: Sheela Prabhu, MD, FACP
Sponsors: Internal FDN
Details (Indentifier #): None
Title: The CHRONICLE Study: A Longitudinal Prospective Observational Study of the Characteristics,Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States, D3250R000023
Department: Pulmonary
Diagnosis: Lung - Asthma
Principal Investigator: Louis R Dubois, MD
Sub-Investigator(s):
Sponsors: Astra Zeneca
Details (Indentifier #): NCT03373045
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